Past Meetings – 1999-2001

July 25, 2001 by  

4th KPro – 6th IOSS Study Group Meeting, Miami, USA
FOCUS: KERATOPROSTHESIS OR NOT

4th KPro STUDY GROUP MEETING
May 4-5, 2001
Fort Lauderdale, Marina Marriott, Florida, USA

 

Date:
May 4-5, 2001

 

Organizer:
Bascom Palmer Eye Institute
University of Miami, School of Medicine
Miami, Florida
USA

 

Venue:
Fort Lauderdale, Marina Marriott, Florida, USA

 

Friday May 4

 

Registration
KPro-IOSS status today & introduction of Dr. Sweeney. Jean-Marie Parel

 

KPro: 34 years later. Michael Roper-Hall

 

Introduction of Prof. T.T. Sun. Scheffer CG Tseng

 

Introduction of Prof. Claes Dohlman. Eduardo Alfonso

 

Session I: KERATOPROSTHESIS
Chair: C Dohlman – Moderator: E Alfonso

 

KPro Study Group Keynote lecture
Do a PK? Do a KPro? Do nothing? The uncertain borders between indications. Claes Dohlman

 

Modified Osteo-odonto-keratoprosthesis for treatment of corneal blindness: Long-term anatomic and functional outcome in 181 cases. Giancarlo C Falcinelli

 

Osteo-odonto-keratoprosthesis. Francesco Lannetti

 

The osteo-odonto-keratoprosthesis – resume of six years operative experience. Konrad Hille

 

Medium term visual and retention results of modern osteo-odonto-keratoprosthesis (OOKP). Padmanabha P Syam

 

A model for international skills transfer for OOKP surgery. Christopher Liu

 

Advantages of self-graft tibial keratoprosthesis (KPT). Jose Temprano Acedo

 

Thirty years of experience with the stainless steel anchored artificial cornea champagne cork KP. Jan G F Worst

 

20 years experience with the Pintucci’s keratoprosthesis. Stefano Pintucci

 

Biocolonization: Early success and late disillusions. Emmanuel Lacombe

 

Experience with Lacombe PCL5 KPro at the Ain Shams Shams University – Egypt. Amira Mounir

 

Chirila KPro I: An overview. Geoffrey J Crawford
Chirila KPro II: Case histories. Donald Tan
Chirila KPro III: Keratoprosthesis or not? Celia R Hicks

 

Results of leukomas biokeratoprosthetics using prostheses with the peripheral part made of various donor tissues. Yury Y Kalinnikov

 

Surgical treatment of secondary glaucoma by keratoprosthesis. Stanislav A Yakimenko


Session II OCULAR SURFACE RECONSTRUCTION

Chair: SCG Tseng – Moderator: K Tsubota

 

IOSS Keynote Lecture:
Corneal epithelial stem cells: Markers, kinetic regulation and development flexibilities. Tung-Tien Sun

 

Restoration of neuroanatomic integration of ocular surface defense as a first step of ocular surface reconstruction. Scheffer CG Tseng

 

Amniotic membrane transplantation associated with limbal conjuctival transplantation for ocular surface reconstruction in Stevens-Johnson syndrome. Jose AP Gomes

 

Amniotic membrane transplantation associated or not with limbal-conjuctival transplantation for ocular surface reconstruction in chemical burn. Myrna S Santos

 

Treatment of severe ocular surface disorders with corneal epithelial stem cell transplantation. Kazuo Tsubota

 

Factors influencing surgical outcome of ocular surface reconstruction. Jun Shimakazi

 

Long-term results of kerarolimbal allografts with or without penetrating keratoplasty for total limbal stem cell deficiency. Abraham Solomon

 

The effect of amniotic membrane and limbal autograft transplantation for the patients with recurrent ptergium and pseudoptergium associated with symblepharon. Tae Hoon Choi

 

Changes in human corneas after amniotic membrane transplantation. A correlative light and transmission electron microscopy study. Josef Stoiber

 

Keratoprosthesis or keratoplasty and surface reconstruction: How to choose? John Dart

 

Saturday May 5

 

Registration

 

Session III OSR & KPro POSTER PRESENTATION
Chair: J Dart – Moderator: G Grabner

 

Surgical management of refractory palpebral allergic conjuctivitis. Quresh B Muskati

 

AMT for unusual corneal deposits in homocystinuria. Srinivas K Rao

 

Histology of non-extruding OOKP laminae. Christopher Liu

 

Can we implant our keratoprosthesis for humans as a temporary use? Hiroshi Shiota

 

Comparison of infection rates in patients following amniotic membrane transplant (AMT) and keratoprosthesis. Eduardo C Alfonso

 

Endophthalmitis in patients with keratoprosthesis: Incidence, bacterial etiologies and risk factors. Mahnaz Nouri

 

Osteo-odonto-keratoprosthesis modified: Long-term results in dry eyes. Giancarlo Falcinelli

 

Retroprosthesis membranes as complications after keratoprosthesis. Stanislav A Yakimenko

 

Evaluation of bone reduction of the haptic lamina in osteo-odonto-keratoprosthesis by computerized tomography. Josef Stoiber

 

Management of vitreoretinal complications in eyes with permanent keratoprosthesis. Subhransu Ray

 

Corneal blindness from end-stage sjorgrens syndrome. Case reports. Eric J Dudenhoefer

 

Long-term results of pump shunt implant for refractory glaucoma. Thomas C White

 

Biointegration of the dacron felt colonizable Pintucci’s keratoprosthesis, in vitro and in vivo studies plan. Stefanno Pintucci

 

Coralline Hydoxyapatite keratoprosthesis. Carlos Leon

 

Keratoprosthesis in a seeing eye – a case report. Quresh B Maskati

 

An in vivo model for assessment of epithelial overgrowth of synthetic onlays. RZ Xie

 

Experiments with keratoprostheis (“Artificial cornea”). Mahnaz Nouri

 

Costs and gains of complex procedures in rehabilitation of end stage Stevens- Johnson syndrome. Gerd Geerling

 

Session IV THE FUTURE: OSR? KPros? Or both?
Chair: JM Parel – Moderator: Ray JF Tsai

 

Introduction of Dr. May Griffith Scheffer CG Tseng
Biocornea Invited Lecture:
Corneal tissue equivalents for replacement of damaged corneas. May Griffith

 

Ex vivo expansion of limbal stem cells for corneal surface reconstruction. Ray Jui-Fang Tsai

 

Cultivated corneal epithelial transplantation in severe stem cell deficiencies. Shigeru Kinoshita

 

The step-wise operation used in vivo grown corneal epithelium on amniotic membrane in patient’s own eye in acute corneal burn injury. Jae Chan Kim

 

Evaluation of the limbus stem cell concept by a gene analytic procedure. Konrad Hille

 

Transplantation of the autologous submandibular gland for absolute dry eyes. Gerd Geerling

 

Development of a newly designed double-fixed Seoul-type keratoprosthesis. Mee Kum Kim

 

How to cope with decolonization and necrosis to prevent extrusion. Emmanuel Lacombe

 

A new supradescemetic keratoprosthesis: A novel design. Stephan Kaminski

 

In vivo examination of surface modified polymers used as potential hap keratoprosthesis. Eike Berger

 

In vivo preliminary screening of novel KPro materials & Towards a synthetic OOKP. Andrew W Lloyd

 

Synthetic polymer as a corneal onlay. Debbie F Sweeney

 

Conclusions: Alfonso, Tseng, Parel, Sweeney


3rd KPro Study Group Meeting, Birmingham, England

3rd KPro STUDY GROUP MEETING

 

June 24-26, 1999
University of Birmingham Conference Park
Birmingham, England
Focus: Role of the haptic in increasing KPro long term survival

 

Meeting Executive President: Michael J. Roper-Hall
Poster Coordination: Peter McDonnell & Kira Brenman
KPro’99 Scientific Coordinator: Kira Brenman

 

“Proceedings may be found An Inst Barraquer 2001, 30 (1-2) :”
Presentations at the 3rd KPro Study Group Meeting

 

Friday June 25, 1999

 

Introduction.
Michael Roper-Hall, University of Birmingham, England

 

Contributions of past KPro conferences and the future.
J-M Parel for the KPro Study Group Steering Committee

 

Early experience and present views on keratoprosthesis.
Joaquin Barraquer, Instituto Barraquer, Spain.

Session I Clinical results of 1st generation KPros
(Monobloc, synthetics)
Chairs: Lacombe & Polack, Moderator: Dohlman

 

Success and failure of 1st generation KPros.
Michael Roper-Hall, University of Birmingham, England

 

KPro in non-cicatrizing conditions.
Claes Dohlman, Mass. Eye and Ear, USA

 

Ceramic KPro, long term follow-up.
Frank Polack, G Heimke, University of Florida, University of South Florida, USA

 

All PMMA retroprosthetic fixation KPro at 10 years.
Emmanuel Lacombe, Rothschild Foundation, France

 

Session II: Clinical results of 2nd generation KPros
(OOKP, biologic skirt)
Chairs: Falcinelli & Barraquer, Moderator: Grabner

 

Falcinelli’s OOKP KPro – 15 years experience.
Giancarlo Falcinelli, P Colliardo, E Corazza, M Taloni, Foundation for OOKP, Italy

 

Long-term success in OOKP: Can VATI give more comparable results? A proposal for a method to compare “Medium to Long-term” outcome as demonstrated by the Salzburg OOKP series.
Gunther Grabner, J Stoiber, J Ruckhofer, G Falcinelli, Eye Clinic Salzburg, Austria

 

Early British results of modern Falcinelli OOKP surgery.
Andrea Sciscio, C Liu, Sussex Eye Hospital/University of Brighton, England

 

OOKP- surgical management and results.
Konrad Hille, H Landau, KW Ruprecht, University of Saarland, Germany

Complications in OOKP.
Maurizio Taloni, G Falcinelli, B Falsini, P Filadoro, V Petitti, OOKP Foundation, Italy

 

A new lens for vitreous and retinal surgery in OOKP patients.
Jeroni Nadal, J Barraquer, Instituto Barraquer, Spain

 

Session III Clinical results of 3nd generation KPros
(Metals & synthetics, donor tissue integration)
Moderator: Kain

 

Evaluation of 46 KPros after 6 years. Follow-up.
Mihai Pop, Emergency Eye Hospital, Romania

 

Worst KPro.
Jan Worst, MV van Andel. Jan Worst Research Group, Holland

 

KPro in terminal stages of edematous bullous keratopathy.
Stanislav A Yakimenko, Filatov Institute of Eye Diseases & Tissue Therapy, Ukraine

 

Visual recovery in Mooren’s ulcer by scleral grafting and KPro.
YP Henry, MJW Zaal, HJ Volker-Dieben, Free University, Netherlands

 

Paralimbal scleral window;
Indu R Singh, Amritsar, India

 

Session IV Clinical results of 4th generation KPros
(Synthetic biointegration)
Chairs: Pintucci, Moderator: Crawford

 

Girard KPro (commented Video).
Louis Girard, Houston, USA (presented in his absence by Parel and Brenman)

 

PMMA/Dacron biointegrated KPro: 19 years experience.
Stefano Pintucci, F Pintucci, A Sarra, Azienda Ospedaliera, S. Giovanni-Addolorata, Centro Oftalmologico Pintucci, Italy

 

Role of hydromechanical fixation in haptic biocolonization.
Emmanuel Lacombe, Rothschild Foundation, France

 

Pilot study of Chirila KPro in humans.
Celia Hicks, GJ Crawford, TV Chirila, X Lou, S Platten, S Vijayasekaran, IJ Constable, Lions Eye Institute,  Australia

 

Aachen KPro – 1st prolonged application.
Norbert I Schrage, S Kompa, S Langefeld, B Kirchhof, University of Aachen, Germany

 

Evaluation of biocolonizable keratoprosthesis in patients with corneal edema.
Isabelle Riss, University of Bordeaux, France

 

Session V Expulsion and methods to prevent it
Chairs: Lacombe & Caldwell, Moderator: Alfonso

 

Risk Factors for endophthalmitis in KPro patients.
Mahnaz Nouri, H Terada, ML Durand, E Alfonso, CH Dohlman, Mass Eye & Ear, USA and Bascom Palmer Eye Institute, USA

 

Transplantation of the autologous submandibular gland for severe keratoconjunctivitis sicca in Stevens-Johnson syndrome.
Gerd Geerling, JRO Collin, IA Cree, MM Matheson, JKG Dart, Moorfields Eye Hospital, England

 

Immunological & biochemical indices of blood in patients with RPM after KPro.
Olga Guseva, L Velichko, T Metelitsina, SA Yakimenko, Filatov Institute of Eye Diseases & Tissue Therapy,  Ukraine

 

Glaucoma following KPro.
Claes Dohlman, Mass. Eye and Ear, USA

 

The Ahmed glaucoma valve in secondary glaucoma in OOKP.
Konrad Hille, H Landau, KW Ruprecht, University of Saarland, Germany

 

Successful treatment of KPro skirt exposure using a transpositional conjunctival-lower eyelid retractor complex flap.
John Cowden, JW Gigantelli, Mason Eye Institute, USA

 

Clinical indications and action mechanisms of amniotic membrane transplantation for ocular surface reconstruction in patients being considered for a keratoprosthesis.
Eduardo C Alfonso, SCG Tseng, Bascom Palmer Eye Institute, USA

 

Saturday June 26, 1999

 

Session VI Research and Future directions
Chairs: Hicks & Duchesne, Moderator: Parel

 

Assessment of Corneal Mechanics of Humans, Pigs and Cats. Comparison with Keratoprosthesis Polymers.
Bernard Duchesne, R Bougaran, D Durand, H Tahi, University of Liege, Belgium; Bascom Palmer Eye Institute, USA

 

Biocompatibility evaluation of new non-porous transparent materials for keratoprosthesis.
Hassan Tahi, B Duchesne, Bascom Palmer Eye Institute, USA; University of Liege, Belgium

 

Ocular biomaterials: Cellular & surface chemical issues.
Brian Tighe, Aston University, Birmingham, UK

 

Development of new synthetic material for corneal replacements.
Valerie Franklin, F Lydon, K Evans, B Tighe, C Liu, Aston University, England

 

Does embryonic keratocyte EK1.BR models corneal wound healing with age?
Susan Sandeman, RGA Faragher, M Allen, C Liu, AW Llyod, University of Brighton, England

 

Effect of aging on KPro biointegration.
Susan Sandeman, RGA Faragher, M Allen, C Liu, AW Llyod, University of Brighton, England

 

In-vitro study of silicone foam and ePTFE as potential haptic materials for KPro
Eike Berger, K Gaebert, J Saedler, CF Kreiner, R Guthoff, University of Rostock, Germany

 

Evaluation of ceramic KPro in rabbits.
Hiroshi Shiota, H Eguchi, H Yunoki, H Amitani, University of Tokushima, Japan

 

Hydroxyapatite coralline keratoprosthesis: First human cases.
Carlos Leon, Guatemala

 

Session VII Summary of poster presentation
Chairs: Falcinelli & Rol, Moderator: Barraquer

 

Clinical results of 1st to 4th generation KPros

 

OOKP in the treatment of corneal blindness due to “dry eye”.
Paulo Colliardo, M Caselli, GC Falcinelli, G Grabner, I Micozzi, Foundation for OOKP, Italy

 

Visual fields with an OOKP.
Chris Hull, DF Edgar, C Liu, A Sciscio, City University, England

 

Influence of PMMA diameter on visual field in OOKP.
Konrad Hille, H Landau, KW Ruprecht, University of Saarland, Germany

 

Design of OOKP optic-improving field of vision.
Chris Hull, DF Edgar, C Liu, A Sciscio, City University, England

 

OOKP: New design of optical cylinder.
Giancarlo Falcinelli, R Fletcher, L Lupelli, P Palumbo, F Sala, Foundation for OOKP, Italy

 

Aachen KPro-1st temporary application.
Sirpa Kompa, S Langefeld, B Kirchhof, NF Schrage, University of Aachen, Germany

 

Posterior fixation keratoprosthesis with biocolonizable seal: 6 years, 47 patients.
Emmanuel Lacombe, J-C Joyaux, I Riss, B Duchesne, H Tahi, J-M Parel, Rothschild Foundation, France & Universities of Miami, Bordeaux, Liege, and Paris

Preoperative prognostic factors in keratoprosthesis.
F Yaghouti, M Nouri, WC Fung, WJ Power, MJ Doane, CH Dohlman. Mass Eye&Ear Infirmary and Schepens Eye Research Institute, USA

 

Research and Future directions

 

Human and porcine cornea.
Katrin Gaebert, E Berger, J Saedler, DG Weiss, R Guthoff, University of Rostock, Germany

 

Cartilage to cornea: structural & cellular issues in material design for KPros.
Fiona Lydon, PH Corkhill, JH Fitton, VJ Franklin, HR Oxley, BJ Tighe, Aston University, England

 

A new prosthetic corneal graft.
Thomas White, University of South Dakota, USA

 

Marine inspired artificial cornea.
David Green, F Lydon, B Tighe, C Liu, Aston University, England

 

Ophthalmic biomaterials: Inflammatory role of vitronectin.
Brian Tighe, VJ Franklin, C Graham, A Mann, M Guillon, Aston University, England

 

Biosurface structures: Nature’s solutions.
Steve Tonge, B Tighe, Aston University, England

 

Aston biomaterials research unit: A profile.
Valerie Franklin et al, Aston University, England

 

Invited presentation: Once upon a time there was a blind.
Jean-Christophe Joyaux, Martinique, FWI


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