Past Meetings – 1999-2001

July 25, 2001 by · Leave a Comment 

4th KPro – 6th IOSS Study Group Meeting, Miami, USA

May 4-5, 2001
Fort Lauderdale, Marina Marriott, Florida, USA


May 4-5, 2001


Bascom Palmer Eye Institute
University of Miami, School of Medicine
Miami, Florida


Fort Lauderdale, Marina Marriott, Florida, USA


Friday May 4


KPro-IOSS status today & introduction of Dr. Sweeney. Jean-Marie Parel


KPro: 34 years later. Michael Roper-Hall


Introduction of Prof. T.T. Sun. Scheffer CG Tseng


Introduction of Prof. Claes Dohlman. Eduardo Alfonso


Chair: C Dohlman – Moderator: E Alfonso


KPro Study Group Keynote lecture
Do a PK? Do a KPro? Do nothing? The uncertain borders between indications. Claes Dohlman


Modified Osteo-odonto-keratoprosthesis for treatment of corneal blindness: Long-term anatomic and functional outcome in 181 cases. Giancarlo C Falcinelli


Osteo-odonto-keratoprosthesis. Francesco Lannetti


The osteo-odonto-keratoprosthesis – resume of six years operative experience. Konrad Hille


Medium term visual and retention results of modern osteo-odonto-keratoprosthesis (OOKP). Padmanabha P Syam


A model for international skills transfer for OOKP surgery. Christopher Liu


Advantages of self-graft tibial keratoprosthesis (KPT). Jose Temprano Acedo


Thirty years of experience with the stainless steel anchored artificial cornea champagne cork KP. Jan G F Worst


20 years experience with the Pintucci’s keratoprosthesis. Stefano Pintucci


Biocolonization: Early success and late disillusions. Emmanuel Lacombe


Experience with Lacombe PCL5 KPro at the Ain Shams Shams University – Egypt. Amira Mounir


Chirila KPro I: An overview. Geoffrey J Crawford
Chirila KPro II: Case histories. Donald Tan
Chirila KPro III: Keratoprosthesis or not? Celia R Hicks


Results of leukomas biokeratoprosthetics using prostheses with the peripheral part made of various donor tissues. Yury Y Kalinnikov


Surgical treatment of secondary glaucoma by keratoprosthesis. Stanislav A Yakimenko


Chair: SCG Tseng – Moderator: K Tsubota


IOSS Keynote Lecture:
Corneal epithelial stem cells: Markers, kinetic regulation and development flexibilities. Tung-Tien Sun


Restoration of neuroanatomic integration of ocular surface defense as a first step of ocular surface reconstruction. Scheffer CG Tseng


Amniotic membrane transplantation associated with limbal conjuctival transplantation for ocular surface reconstruction in Stevens-Johnson syndrome. Jose AP Gomes


Amniotic membrane transplantation associated or not with limbal-conjuctival transplantation for ocular surface reconstruction in chemical burn. Myrna S Santos


Treatment of severe ocular surface disorders with corneal epithelial stem cell transplantation. Kazuo Tsubota


Factors influencing surgical outcome of ocular surface reconstruction. Jun Shimakazi


Long-term results of kerarolimbal allografts with or without penetrating keratoplasty for total limbal stem cell deficiency. Abraham Solomon


The effect of amniotic membrane and limbal autograft transplantation for the patients with recurrent ptergium and pseudoptergium associated with symblepharon. Tae Hoon Choi


Changes in human corneas after amniotic membrane transplantation. A correlative light and transmission electron microscopy study. Josef Stoiber


Keratoprosthesis or keratoplasty and surface reconstruction: How to choose? John Dart


Saturday May 5




Chair: J Dart – Moderator: G Grabner


Surgical management of refractory palpebral allergic conjuctivitis. Quresh B Muskati


AMT for unusual corneal deposits in homocystinuria. Srinivas K Rao


Histology of non-extruding OOKP laminae. Christopher Liu


Can we implant our keratoprosthesis for humans as a temporary use? Hiroshi Shiota


Comparison of infection rates in patients following amniotic membrane transplant (AMT) and keratoprosthesis. Eduardo C Alfonso


Endophthalmitis in patients with keratoprosthesis: Incidence, bacterial etiologies and risk factors. Mahnaz Nouri


Osteo-odonto-keratoprosthesis modified: Long-term results in dry eyes. Giancarlo Falcinelli


Retroprosthesis membranes as complications after keratoprosthesis. Stanislav A Yakimenko


Evaluation of bone reduction of the haptic lamina in osteo-odonto-keratoprosthesis by computerized tomography. Josef Stoiber


Management of vitreoretinal complications in eyes with permanent keratoprosthesis. Subhransu Ray


Corneal blindness from end-stage sjorgrens syndrome. Case reports. Eric J Dudenhoefer


Long-term results of pump shunt implant for refractory glaucoma. Thomas C White


Biointegration of the dacron felt colonizable Pintucci’s keratoprosthesis, in vitro and in vivo studies plan. Stefanno Pintucci


Coralline Hydoxyapatite keratoprosthesis. Carlos Leon


Keratoprosthesis in a seeing eye – a case report. Quresh B Maskati


An in vivo model for assessment of epithelial overgrowth of synthetic onlays. RZ Xie


Experiments with keratoprostheis (“Artificial cornea”). Mahnaz Nouri


Costs and gains of complex procedures in rehabilitation of end stage Stevens- Johnson syndrome. Gerd Geerling


Session IV THE FUTURE: OSR? KPros? Or both?
Chair: JM Parel – Moderator: Ray JF Tsai


Introduction of Dr. May Griffith Scheffer CG Tseng
Biocornea Invited Lecture:
Corneal tissue equivalents for replacement of damaged corneas. May Griffith


Ex vivo expansion of limbal stem cells for corneal surface reconstruction. Ray Jui-Fang Tsai


Cultivated corneal epithelial transplantation in severe stem cell deficiencies. Shigeru Kinoshita


The step-wise operation used in vivo grown corneal epithelium on amniotic membrane in patient’s own eye in acute corneal burn injury. Jae Chan Kim


Evaluation of the limbus stem cell concept by a gene analytic procedure. Konrad Hille


Transplantation of the autologous submandibular gland for absolute dry eyes. Gerd Geerling


Development of a newly designed double-fixed Seoul-type keratoprosthesis. Mee Kum Kim


How to cope with decolonization and necrosis to prevent extrusion. Emmanuel Lacombe


A new supradescemetic keratoprosthesis: A novel design. Stephan Kaminski


In vivo examination of surface modified polymers used as potential hap keratoprosthesis. Eike Berger


In vivo preliminary screening of novel KPro materials & Towards a synthetic OOKP. Andrew W Lloyd


Synthetic polymer as a corneal onlay. Debbie F Sweeney


Conclusions: Alfonso, Tseng, Parel, Sweeney

3rd KPro Study Group Meeting, Birmingham, England



June 24-26, 1999
University of Birmingham Conference Park
Birmingham, England
Focus: Role of the haptic in increasing KPro long term survival


Meeting Executive President: Michael J. Roper-Hall
Poster Coordination: Peter McDonnell & Kira Brenman
KPro’99 Scientific Coordinator: Kira Brenman


“Proceedings may be found An Inst Barraquer 2001, 30 (1-2) :”
Presentations at the 3rd KPro Study Group Meeting


Friday June 25, 1999


Michael Roper-Hall, University of Birmingham, England


Contributions of past KPro conferences and the future.
J-M Parel for the KPro Study Group Steering Committee


Early experience and present views on keratoprosthesis.
Joaquin Barraquer, Instituto Barraquer, Spain.

Session I Clinical results of 1st generation KPros
(Monobloc, synthetics)
Chairs: Lacombe & Polack, Moderator: Dohlman


Success and failure of 1st generation KPros.
Michael Roper-Hall, University of Birmingham, England


KPro in non-cicatrizing conditions.
Claes Dohlman, Mass. Eye and Ear, USA


Ceramic KPro, long term follow-up.
Frank Polack, G Heimke, University of Florida, University of South Florida, USA


All PMMA retroprosthetic fixation KPro at 10 years.
Emmanuel Lacombe, Rothschild Foundation, France


Session II: Clinical results of 2nd generation KPros
(OOKP, biologic skirt)
Chairs: Falcinelli & Barraquer, Moderator: Grabner


Falcinelli’s OOKP KPro – 15 years experience.
Giancarlo Falcinelli, P Colliardo, E Corazza, M Taloni, Foundation for OOKP, Italy


Long-term success in OOKP: Can VATI give more comparable results? A proposal for a method to compare “Medium to Long-term” outcome as demonstrated by the Salzburg OOKP series.
Gunther Grabner, J Stoiber, J Ruckhofer, G Falcinelli, Eye Clinic Salzburg, Austria


Early British results of modern Falcinelli OOKP surgery.
Andrea Sciscio, C Liu, Sussex Eye Hospital/University of Brighton, England


OOKP- surgical management and results.
Konrad Hille, H Landau, KW Ruprecht, University of Saarland, Germany

Complications in OOKP.
Maurizio Taloni, G Falcinelli, B Falsini, P Filadoro, V Petitti, OOKP Foundation, Italy


A new lens for vitreous and retinal surgery in OOKP patients.
Jeroni Nadal, J Barraquer, Instituto Barraquer, Spain


Session III Clinical results of 3nd generation KPros
(Metals & synthetics, donor tissue integration)
Moderator: Kain


Evaluation of 46 KPros after 6 years. Follow-up.
Mihai Pop, Emergency Eye Hospital, Romania


Worst KPro.
Jan Worst, MV van Andel. Jan Worst Research Group, Holland


KPro in terminal stages of edematous bullous keratopathy.
Stanislav A Yakimenko, Filatov Institute of Eye Diseases & Tissue Therapy, Ukraine


Visual recovery in Mooren’s ulcer by scleral grafting and KPro.
YP Henry, MJW Zaal, HJ Volker-Dieben, Free University, Netherlands


Paralimbal scleral window;
Indu R Singh, Amritsar, India


Session IV Clinical results of 4th generation KPros
(Synthetic biointegration)
Chairs: Pintucci, Moderator: Crawford


Girard KPro (commented Video).
Louis Girard, Houston, USA (presented in his absence by Parel and Brenman)


PMMA/Dacron biointegrated KPro: 19 years experience.
Stefano Pintucci, F Pintucci, A Sarra, Azienda Ospedaliera, S. Giovanni-Addolorata, Centro Oftalmologico Pintucci, Italy


Role of hydromechanical fixation in haptic biocolonization.
Emmanuel Lacombe, Rothschild Foundation, France


Pilot study of Chirila KPro in humans.
Celia Hicks, GJ Crawford, TV Chirila, X Lou, S Platten, S Vijayasekaran, IJ Constable, Lions Eye Institute,  Australia


Aachen KPro – 1st prolonged application.
Norbert I Schrage, S Kompa, S Langefeld, B Kirchhof, University of Aachen, Germany


Evaluation of biocolonizable keratoprosthesis in patients with corneal edema.
Isabelle Riss, University of Bordeaux, France


Session V Expulsion and methods to prevent it
Chairs: Lacombe & Caldwell, Moderator: Alfonso


Risk Factors for endophthalmitis in KPro patients.
Mahnaz Nouri, H Terada, ML Durand, E Alfonso, CH Dohlman, Mass Eye & Ear, USA and Bascom Palmer Eye Institute, USA


Transplantation of the autologous submandibular gland for severe keratoconjunctivitis sicca in Stevens-Johnson syndrome.
Gerd Geerling, JRO Collin, IA Cree, MM Matheson, JKG Dart, Moorfields Eye Hospital, England


Immunological & biochemical indices of blood in patients with RPM after KPro.
Olga Guseva, L Velichko, T Metelitsina, SA Yakimenko, Filatov Institute of Eye Diseases & Tissue Therapy,  Ukraine


Glaucoma following KPro.
Claes Dohlman, Mass. Eye and Ear, USA


The Ahmed glaucoma valve in secondary glaucoma in OOKP.
Konrad Hille, H Landau, KW Ruprecht, University of Saarland, Germany


Successful treatment of KPro skirt exposure using a transpositional conjunctival-lower eyelid retractor complex flap.
John Cowden, JW Gigantelli, Mason Eye Institute, USA


Clinical indications and action mechanisms of amniotic membrane transplantation for ocular surface reconstruction in patients being considered for a keratoprosthesis.
Eduardo C Alfonso, SCG Tseng, Bascom Palmer Eye Institute, USA


Saturday June 26, 1999


Session VI Research and Future directions
Chairs: Hicks & Duchesne, Moderator: Parel


Assessment of Corneal Mechanics of Humans, Pigs and Cats. Comparison with Keratoprosthesis Polymers.
Bernard Duchesne, R Bougaran, D Durand, H Tahi, University of Liege, Belgium; Bascom Palmer Eye Institute, USA


Biocompatibility evaluation of new non-porous transparent materials for keratoprosthesis.
Hassan Tahi, B Duchesne, Bascom Palmer Eye Institute, USA; University of Liege, Belgium


Ocular biomaterials: Cellular & surface chemical issues.
Brian Tighe, Aston University, Birmingham, UK


Development of new synthetic material for corneal replacements.
Valerie Franklin, F Lydon, K Evans, B Tighe, C Liu, Aston University, England


Does embryonic keratocyte EK1.BR models corneal wound healing with age?
Susan Sandeman, RGA Faragher, M Allen, C Liu, AW Llyod, University of Brighton, England


Effect of aging on KPro biointegration.
Susan Sandeman, RGA Faragher, M Allen, C Liu, AW Llyod, University of Brighton, England


In-vitro study of silicone foam and ePTFE as potential haptic materials for KPro
Eike Berger, K Gaebert, J Saedler, CF Kreiner, R Guthoff, University of Rostock, Germany


Evaluation of ceramic KPro in rabbits.
Hiroshi Shiota, H Eguchi, H Yunoki, H Amitani, University of Tokushima, Japan


Hydroxyapatite coralline keratoprosthesis: First human cases.
Carlos Leon, Guatemala


Session VII Summary of poster presentation
Chairs: Falcinelli & Rol, Moderator: Barraquer


Clinical results of 1st to 4th generation KPros


OOKP in the treatment of corneal blindness due to “dry eye”.
Paulo Colliardo, M Caselli, GC Falcinelli, G Grabner, I Micozzi, Foundation for OOKP, Italy


Visual fields with an OOKP.
Chris Hull, DF Edgar, C Liu, A Sciscio, City University, England


Influence of PMMA diameter on visual field in OOKP.
Konrad Hille, H Landau, KW Ruprecht, University of Saarland, Germany


Design of OOKP optic-improving field of vision.
Chris Hull, DF Edgar, C Liu, A Sciscio, City University, England


OOKP: New design of optical cylinder.
Giancarlo Falcinelli, R Fletcher, L Lupelli, P Palumbo, F Sala, Foundation for OOKP, Italy


Aachen KPro-1st temporary application.
Sirpa Kompa, S Langefeld, B Kirchhof, NF Schrage, University of Aachen, Germany


Posterior fixation keratoprosthesis with biocolonizable seal: 6 years, 47 patients.
Emmanuel Lacombe, J-C Joyaux, I Riss, B Duchesne, H Tahi, J-M Parel, Rothschild Foundation, France & Universities of Miami, Bordeaux, Liege, and Paris

Preoperative prognostic factors in keratoprosthesis.
F Yaghouti, M Nouri, WC Fung, WJ Power, MJ Doane, CH Dohlman. Mass Eye&Ear Infirmary and Schepens Eye Research Institute, USA


Research and Future directions


Human and porcine cornea.
Katrin Gaebert, E Berger, J Saedler, DG Weiss, R Guthoff, University of Rostock, Germany


Cartilage to cornea: structural & cellular issues in material design for KPros.
Fiona Lydon, PH Corkhill, JH Fitton, VJ Franklin, HR Oxley, BJ Tighe, Aston University, England


A new prosthetic corneal graft.
Thomas White, University of South Dakota, USA


Marine inspired artificial cornea.
David Green, F Lydon, B Tighe, C Liu, Aston University, England


Ophthalmic biomaterials: Inflammatory role of vitronectin.
Brian Tighe, VJ Franklin, C Graham, A Mann, M Guillon, Aston University, England


Biosurface structures: Nature’s solutions.
Steve Tonge, B Tighe, Aston University, England


Aston biomaterials research unit: A profile.
Valerie Franklin et al, Aston University, England


Invited presentation: Once upon a time there was a blind.
Jean-Christophe Joyaux, Martinique, FWI