Special Interest at ARVO
September 29, 2008 by admin · Leave a Comment
The ARVO 2008 Annual Meeting, Eyes on Innovation, was held on April 27-May 1 in Fort Lauderdale, Florida.
The KPro group took advantage of this major meeting to hold a Special Interest Group focused on Keratoprostheses and Glaucoma. The session looked at new technologies associated with corneal prostheses including challenges, advancements and problems, with a special focus on glaucoma.
ARVO is a major forum for vision researchers and practitioners to explore the latest innovative techniques, protocols and tools in development and use by ophthalmic researchers whose quest is to improve patient care and vision and to cure eye diseases.
The SIG attracted many attendees in what proved to be a very interesting session.
The SIG was moderated by Claes Dohlman, Harvard Medical School, and Jean-Marie Parel, Bascom Palmer Eye Institute, University of Miami.
The SIG included presentations from:
- Victor Perez: Opening comments & KPro’s today – types of implants, indications and problems with Glaucoma
- Konrad Hille: Intraocular pressure measurements post KPro implantation
- Cynthia Grosskreutz: Incidence and treatment options
- Yale Fisher: Endoscopy & KPro
- Paul Palmberg: Drainage implants
Evaluation of the Stability of Boston Keratoprosthesis Type I – Donor Cornea Interface Utilizing Anterior Segment Optical Coherence Tomography
September 29, 2008 by admin · Leave a Comment
Author Block: J.P. Garcia, Jr.1A,2, D.C. Ritterband1,2, A. Ko1,2, J.A. Seedor1,2, D.F. Buxton1,2, J. De la Cruz3. ARetina Center, 1New York Eye & Ear Infirmary, New York, NY; 2New York Medical College, Valhalla, NY; 3Illinois Eye & Ear Infirmary, Chicago, IL.
Purpose: To evaluate the anatomic stability of an implanted Boston Type I Keratoprosthesis (KPro)-donor cornea interface, and assess the presence or absence of a potential space (gap) between the KPro front plate and donor cornea using anterior segment optical coherence tomography (AS- OCT). The presence of a gap would raise concerns of a possible pathway for the exchange of fluid between the ocular surface and the anterior chamber.
Methods: Fourteen eyes implanted with a Boston Type I KPro were studied by the non-contact technique of AS-OCT (AC Cornea OCT prototype, OTI, Canada). All the KPro devices had been implanted at least 4 weeks prior to the study (range: 1 to 22 months). Seven eyes had aphakic Kpros and the other 7 had pseudophakic implants. Anesthetized eyes were imaged before and during pressure application using sterile cotton tip applicators. Pressure was applied for 10 seconds just outside the temporal limbal area. Images were analyzed for any possible changes in the KPro-donor cornea interface during the application of pressure.
Results: Of 14 eyes, 10 had the threaded front plate model with a T-shaped silhouette and corrugated sides, whereas 4 had the threadless type with a T-shaped silhouette and smooth sides on cross-sectional OCT. Two of the 14 eyes revealed a gap between the front plate and the surface of the donor cornea, along with pooling of fluorescein within the gap. The rest revealed no gaps. With pressure, none of the eyes, including the two with gaps, demonstrated any change in the KPro-donor cornea interface during dynamic imaging (e.g. gaping, evidence of fluid entry or escape along the KPro-donor cornea borders). In all eyes, the titanium locking ring was visualized in its proper position.
Conclusions: The stability of an implanted KPro-donor cornea interface has been demonstrated dynamically utilizing AS-OCT. A gap that has been documented with this imaging tool showed neither extension nor exchange of fluid between the two environments during dynamic cross sectional imaging. All 14 eyes demonstrated proper positioning of the back plate and titanium locking ring, thus confirming that the phenomenon is not due to a loose fitting, unscrewing or improperly placed locking ring. Further studies will be needed to assess the cause of these gaps and determine if they are possibly related to the hydration status of the cornea, interaction of the cornea with prolonged use of a bandage contact lens or to other factors not yet determined.
Commercial Relationship: J.P. Garcia, OPKO, R; D.C. Ritterband, None; A. Ko, None; J.A. Seedor, None; D.F. Buxton, None; J. De la Cruz, None.
KPro SIS at EVER Conference, Portoroz, Slovenia
September 24, 2008 by admin · Leave a Comment
| KPro SIS at EVER Conference, Portoroz, Slovenia | ||
| Date: | Saturday 4th October 2008 | |
| Location: | Room – Emerald I | |
| Time: | 14:15-15:45 hrs | |
| Special Interest Symposium (Keratoprostheses I) | ||
| Moderator: | Christopher Liu | |
| 14:15-14:33 | The narrowing choice of Keratoprostheses | Liu C |
| 14:33-14:51 | Developing a recovery psychological model for patients undergoing KPro surgery | Busuttil A, Liu C |
| 14:51-15:09 | More than 50 years experience with keratoprostheses | Barraquer J |
| 15:09-15:27 | Biosynthetic corneas – an update | Fagerholm P, Lagali N, Griffith M |
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Past Meetings – 2008-2005
July 24, 2008 by admin · Leave a Comment
| Date: | Saturday 6th October 2007 | |
| Location: | Room – Europa A | |
| Time: | 14:00-15:30 hrs | |
| Special Interest Symposium (Keratoprosthesis II) | ||
| Moderator: | Christopher Liu | |
| 14:00-14:15 | Advances in the Type I Boston Keratoprosthesis | Colby K, Dohlmann C |
| 14:15-14:30 | Boston KPro Collaborative Study Results | Belin MW |
| 14:30-14:45 | An Update on the AlphaCor | Crawford G, Hicks C |
| 14:45-15:00 | Where are we with the Supra-Descemetic KPro (Keralia)? | Lamar PD, Alfonso E, Stoiber J, Fernandez V, Kaminski S, Lacombe E, Duchesne B, Acosta C, Parel JM |
| 15:00-15:15 | An Update on the Synthetic Collagenous Artificial Cornea | Fagerholm P, Griffith M |
| 15:15-15:30 | Infection Control in KPro’s | Nouri M |
| For further information and conference details please go to: http://www.ever.be/news.php | ||
Corneal Bioengineering Special Interest Symposia at the European Association for Vision & Eye Research (EVER) Conference
Date:
Saturday 7th October 2006
Location:
Vilamoura, Portugal
For further conference and program details, please go to: http://www.ever.be
KPro Symposium: The 111th Annual Meeting of the Japanese Ophthalmological Society
Date:
Thursday April 19 to Sunday April 22, 2007
Location:
Osaka International Convention Center, Osaka, Japan
Agenda:
To be posted on this website in due course
Organizers:
Masahiko Fukuda and Christopher Liu
Presentations By:
- Keralia by Prof. Jean-Marie Parel, Bascom Palmer Eye Institute
- ALPHACOR by Assoc. Prof. Geoffrey Crawford, Lions Eye Institute
- ALPHACOR in Japan by Dr. Hiroshi Eguchi, Tokushima University
- OOKP by Mr. Christopher Liu, Sussex Eye Hospital
- OOKP in Japan by Dr. Masahiko Fukuda, Kinki University
Hotel Details:
Rhiga Royal Hotel Osaka
5-3-68, Nakanoshima,
Kita-ku, Osaka 530-0005, Japan
Tel: +81-6-6448-1121
Fax: +81-6-6448-4414
Website: http://www.rihga.co.jp/osaka/index.html
Registration Details:
On site registration only for oveasea attendees
Conference Organiser Contact Details:
Masahiko Fukuda, MD, Dsc.
Assistant Professor,
Department of Ophthalmology,
Kinki University School of Medicine,
377-2, Ohno-Higashi, Osaka-Sayama City,
Osaka 589-8511
Japan
Email: fukuda@ganka.med.kindai.ac.jp
Tel: +81-723-66-0221 (Ext 3234)
Fax: +81-723-68-2559
Please click here to download overview of the symposium 
| Update on Keratoprosthesis to be held at the International Society of Ocular Trauma (ISOT) Conference | |
| Date of Conference: | 29th June – 1st July 2006 |
| Date of KPro Update: | 30th June 2006 |
| Location: | Rome, Italy |
| Abstract Submission Deadline: | 30th March 2006 |
| Early Bird Registration Closes: | 30th March 2006 |
| Scientific Secretariat: | C. Forlini – P. Rossini – S.Dolce – A.Aversano – F.Galli |
| Viale V. Randi 43, 48100 Ravenna (Italy) | |
| Fax: | +39/0544 280049 |
| E-mail: | scientific@isot2006rome.org |
| See attached link for full program details: | http://www.isot2006rome.org/start.php |
6th KPro Study Group Meeting, Miami, Florida, USA
Date:
Saturday 6th May 2006
Venue:
Retter Audiotorium, Bascom Palmer Eye Institute, University of Miami
Program Committee:
Eduardo Alfonso, Jean-Marie Parel, Gunther Grabner, Claes Dohlman, Debbie Sweeney
Meeting Presdient:
Gunther Grabner
Theme:
Biocompatibility and Keratoprosthesis
Objective:
The main object of this meeting will be to review progress of the various keratoprothesis currently being used, look at the development of new devices and gain new knowledge in the area of biocompatibility of keratoprosthesis and how it may be enhanced/improved. Particular emphasis will be placed on understanding corneal stromal interactions.
| 6TH KPRO STUDY GROUP PROGRAM : SATURDAY 6TH MAY 2006 Retter Auditorium, University of Miami, Florida |
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| MODERATOR: Jean Marie Parel |
Timings | Name | Institution | Abstract Title |
| 07:30-08:25 | Registration & Breakfast | |||
| 08:25-08:30 | Welcome & Introductions | Gunther Grabner & Jean-Marie Parel | ||
| 1 | 08:30-08:40 | Giancarlo Falcinelli | OOKP Foundation, Rome, Italy | Modified Osteo-Odonto-Keratoprosthesis: Long Term Results in Dry Eye |
| 2 | 08:40-08:50 | Maria Fideliz de la Paz (Victor Charoenrook) | Barraquer Eye Institute | Functional and Anatomical Results of Keratoprosthesis Using Tooth and Tibia Autograft: A Review of our Experience in Spain |
| 3 | 08:50-09:00 | Gerard Ainsworth | Sussex Eye Hospital | OOKP Surgery in Brighton – 10 Years On |
| 4 | 09:00-09:10 | Donald Tan | Singapore National Eye Center | Osteo-Odonto-Keratoprosthesis Surgery in Asian Eyes – The Singapore Experience |
| 5 | 09:10-09:20 | Paolo Colliardo (Giovanni Falcinelli) | OOKP Foundation, Rome, Italy | Treatment of Retinal Detachment in Modified Osteo-Odonto-Keratoprosthesis |
| 6 | 09:20-09:30 | Konrad Hille | Augenklinik Klinikum Offenburg | Update of Kpro Results in Homburg (Saar) |
| Group Discussion | 09:30-10:15 | |||
| MORNING TEA | 10:15-10:45 | |||
| MODERATOR: Gunther Gabner |
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| 7 | 10:45-10:55 | Bilal F Khan | Massachusetts Eye & Ear Infirmary in Boston | Retention of the Boston Keratoprosthesis |
| 8 | 10:55-11:05 | Brian Zerbe |
Albany Medical Centre | Results from the Multi-Center Boston Keratoprosthesis Type 1 Study Group |
| 9 | 11:05-11:15 | Kalliopi Stasi | Rochester Eye Institute & Center for Visual Sciences, University of Rochester | Evaluation and Comparison of Wavefront Higher Order Aberrations in Dohlman/Boston Keratoprosthesis and Normal Eyes |
| 10 | 11:15:11:25 | Matilda Chan (Kali Stasi) | University of Rochester | Vitreoretinal Surgery Concurrent with Placement of the Dohlman/Boston Keratoprosthesis |
| 11 | 11:25-11:35 | Esen Akpek | The Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore | Keratoprostheses for pediatric cases |
| Group Discussion | 11:35-12:20 | |||
| MODERATOR: Eddie Alfonso |
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| 12 | 12:20-12:30 | Gunther Grabner | Ophthalmology & Optometry, Paracelsus Medical Uni, Alzburg, Austria | The Visual Acuity by Time (VAT) – Index and a New Database for the Evaluation of Mid and Long Term Visual Acuity Following KPro Surgery |
| 13 | 12:30-12:40 | Claes Dohlman | Massachusetts Eye and Ear Infirmary | Attrition and retention – what data we should be collecting |
| Group Discussion | 12:40-13:00 | |||
| LUNCH | 13:00-14:00 | |||
| MODERATOR: Claes Dohlman |
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| 14 | 14:00-14:10 | Tim Hughes | CSIRO Molecular Sciences & Vision CRC, Australia | Synthetic Corneal Onlays and Inlays: Learnings Applicable to Keratoprostheses |
| 15 | 14:10-14:20 | Masahiko Fukuda | Dept of Ophthalmology, Kinki University School of Medicine, Japan | Long Term Survival and Histological Study of Our Original Keratoprosthesis |
| 16 | 14:20-14:30 | Carlos Leon | Clinica Leon / Instituto de Cirugia Ocular | The Hydroxyapatite Kpro |
| 17 | 14:30-14:40 | Celia Hicks (Gunther Grabner) | Lions Eye Institute | AlphaCor: Current Data and Overview of Biocompatibility |
| 18 | 14:40-14:50 | Hiroshi Eguchi | Dept of Vis. Neu. Sci. Sch of Medicine, University of Tokushima | Preliminary outcomes of AlphaCor implantations in Japan.Utility of optical coherence tomography in clinical follow-up of the AlphaCor |
| 19 | 14:50-15:00 | Alireza Ghaffariyeh | Iran Polymer and Petrochemical Institute | Evaluation of Cell Behaviour onto Collagen Grafted Poly (HEMA-co-MAA): In Vitro |
| 20 | 15:00-15:10 | Debbie Sweeney | Vision CRC, Australia | Corneal Inlays – Current Progress |
| Group Discussion | 15:10-15:30 | |||
| AFTERNOON TEA | 15:30-16:00 | |||
| MODERATOR: Debbie Sweeney |
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| 21 | 16:00-16:10 | Radhika Tandon (Vishal Jhanji) | RP Centre for Ophthalmic Sciences, AIIMS, India | Setting up a Keratoprosthesis Service in a Tertiary Care Referral Hospital in India |
| Group Discussion & Close of Meeting | 16:10-17:00 | |||
Registration Fee:
US$50 to cover meeting expenses. Cash payable on the day.
Download Registration Form – 46KB (Microsoft Office Word file – doc)
Driving Instructions to Retter Auditorium: Download PDF
Suggested Hotels:
Intercontinental and Marriot Biscayne Bay (downtown Miami); Sonesta Beach and Ritz Carlton (Key Biscayne). Please note that all speakers will need to make their own travel arrangements and hotel bookings.
| World Ophthalmology Congress, 19-24 February 2006, Sao Paulo, Brazil | ||
| Location: | São Paulo, Brazil | |
| Venue: | Transamerica Hotel & Convention Center, Sao Paulo, Brazil | |
| Session Organiser: | Dr Christopher Liu | |
| Session Chair: | Dr Radhika Tandon, Dr Lucio Dantas, Dr Sidney Julio De Faria | |
| Date of Session: | 21st February 2006 | |
| Time of Session: | 08:30-10:30 hrs | |
| Keratoprosthesis Session | ||
| 08:30 hrs | 14 Years Experience with Brazilian Biocolonizable Keratoprothesis | Lucio Dantas |
| 08:40 hrs | Setting up a Keratoprosthesis Service in a Tertiary Care | Radhika Tandon |
| Referral Hospital in India | ||
| 08:50 hrs | The Pintucci KPro | Quresh Maskati |
| 09:00 hrs | AlphaCor Implantation | Geoff Crawford |
| 09:10 hrs | AlphaCor Outcomes | Celia Hicks |
| 09:20 hrs | Discussion | |
| 09:30 hrs | OOKP – The Singapore Experience | Donald Tan |
| 09:40 hrs | Theoretical Considerations of Glaucoma Shunts in Eyes with | Keith Barton |
| Keratoprostheses | ||
| 09:50 hrs | Multi-center Study Results for the Boston K-Pro | Michael Belin |
| 10:00 hrs | Keralia – Early Clinical Outcome | Peggy Lamar |
| 10:10 hrs | Infections and Kpro | Eduardo Alfonso |
| 10:20 hrs | Discussion | |
| 10:30 hrs | End of Symposium |
For further information pertaining to this conference, please go to: http://www.ophthalmology2006.com.br/
Keratoprosthesis SIS at European Association for Vision & Eye Research (EVER) Conference, Vilamoura, Portugal
Date:
Saturday 8th October 2005
Time:
11:00-12:30 hrs
Venue:
Gemini I, Marinotel Hotel, Vilamoura, Portugal
Further program and conference details can be found at www.ever.be
KPro SIS at EVER Conference, Portoroz, Slovenia
July 24, 2008 by admin · Leave a Comment
| Date: | Saturday 4th October 2008 | |
| Location: | Room – Emerald I | |
| Time: | 14:15-15:45 hrs | |
| Special Interest Symposium (Keratoprostheses I) | ||
| Moderator: | Christopher Liu | |
| 14:15-14:33 | The narrowing choice of Keratoprostheses | Liu C |
| 14:33-14:51 | Developing a recovery psychological model for patients undergoing KPro surgery | Busuttil A, Liu C |
| 14:51-15:09 | More than 50 years experience with keratoprostheses | Barraquer J |
| 15:09-15:27 | Biosynthetic corneas – an update | Fagerholm P, Lagali N, Griffith M |
In Memoriam – Dr Frank Polack
July 24, 2008 by admin · Leave a Comment
On July 15 2007 Dr. Frank Polack, our colleague and friend, passed away. Frank was born and raised in Lima, Peru, and received his MD degree in 1954 from San Marcos University. After his graduation he emigrated to the United States, where he did his internship and began a residency in Neuropsychiatry at Grasslands Hospital, Valhalla, NY, a subsidiary of New York University Medical School. In 1956 he was married by proxy, his brother standing in for him, to his childhood sweetheart, Patricia Garcia, then Secretary to American Ambassador to Peru, who soon joined him in New York.
His contact with Dr. Ramon Castroviejo, the world-renowned pioneer in corneal surgery, had persuaded him to change his career choice to ophthalmology, and in 1957, he began his training at Grasslands under Dr. AG ‘‘Gerry” Devoe, then Chair at NYU, who was also a pioneer in corneal surgery. On completion of his residency in 1960, he began an NIH Fellowship under Dr George Smelser at the Eye Institute at Columbia, where he remained for 7 years, during which time he published his groundbreaking studies on electron microscopy of the eye.
Frank joined the faculty at SUNY HSCB where he formed a close personal association with Dr. Donald Willard, with whom he founded the American Ophthalmic Microsurgery Study Club in 1980. In 1967, he left New York to join Dr Herbert Kaufman at the University of Florida, where he continued his clinical and research interests in the cornea, reaching the rank of professor, as well as appointments as adjunct professor in the departments of veterinary medicine and of anatomy.
It was in May 1975 at the PAAO Meeting in San Juan, Puerto Rico, that Frank organized a meeting of a group of former students and associates and colleagues of Dr Ramon Castroviejo and proposed to form a society devoted exclusively to the cornea, to be called the Castroviejo Society (renamed the Cornea Society in 2002). Frank, as principal architect of the society, was elected secretary-treasurer and the first meeting was held during the 1975 AAOO meeting in Dallas, TX. In 1978, Frank founded the journal Cornea, the official journal of the society and the first peer-reviewed journal devoted to the cornea. He remained its editor in chief until 1991.
Frank was a frequent lecturer at national and international meetings and courses. Over his career, he published 180 peer reviewed papers, 5 books, and 12 book chapters on electron microscopy, immunology and corneal transplantation, external disease, and microsurgery of the eye.
In 1980, he left full-time academic medicine and entered private practice in Gainesville. Pat continued to work closely with him in his office, on the journal, and on his continuing publications until his retirement in 2001. In 2005 he was awarded the World Congress Medal, the highest honor of the World Corneal Congress V sponsored by the Cornea Society, in recognition of his many clinical and scientific contributions to the subspecialty, and in particular for his seminal role in the founding of the Castroviejo Society, and the journal Cornea.
Frank is survived by his wife of 51 years, Patricia; 3 sons, Frank E., Peter, a specialist in cornea and refractive surgery, and William; and 4 grandsons.
What is The KPro Study Group?
April 10, 2008 by admin · Leave a Comment
The KPro Study Group was established in 1990 to foster clinical and basic research on keratoprosthesis, synthetic corneas and artificial corneal implants. This International Group aims to foster the development and improvement of keratoprosthesis worldwide for the benefit of eyecare and our patients. The Group is comprised of researchers and surgeons involved in this specialized field, and regular conferences are held to facilitate communication and research development.
Past Meetings – 2004-2002
July 24, 2004 by admin · Leave a Comment
American Academy of Ophthalmology, New Orleans, 22-27 October 2004
Date: Sunday 24th October 2004
Time: 15:15 – 17:30 hrs
Title: All You Wanted to Know About Keratoprosthesis (Artificial Cornea)
Artificial cornea, or keratoprosthesis (KPros), are recommended for restoring sight in corneal blindness where penetrating keratoplasty is contraindicated. Patients who have had multiple corneal graft failure and severe corneal vascularization form one group of prospective KPro candidates. The other group has severe ocular surface disease so that a corneal graft will meet the same fate as the cornea it set out to replace. The course will cover the indications and contraindications, and the pros and cons of a range of Kpros. Patient assessment will be covered. Recognizing complications and how they should be dealt with will also be covered.
The course will impart basic knowledge on the assessment of these prospective keratoprosteses cases prior to referral to a specialist center. Attendees will have a broad understanding of complications of KPros, which will facilitate co-management with specialist surgeons.
Instructors:
Christopher Liu
Gunther Grabner
Giancarlo Falcinelli
Claes Dohlman
Deborah Sweeney
Eduardo Alfonso
Emmanuel Lacombe
Konrad Hille
Geoffrey Crawford
Celia Hicks
Josef Stoiber
Jean-Marie Parel
| EUROPEAN ASSOCIATION FOR VISION AND EYE RESEARCH CONGRESS Date: September 24-27, 2004 Venue: Vilamoura, Portugal |
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| EVER 2004 KPro Special Interest SymposiaDate: September 25, 2004 Venue: Vilamoura, PortugalPlease go the EVER website and submit abstracts to the website marked for the KPro SIS.
Those participating are still required to register at http://www.ever.be. |
OSTEO-ODONTOKERATOPROSTHESIS FOUNDATION PRESENTS:
Surgery of Corneal Opacities: from excimer laser to osteo-odonto-Keratoprosthesis
Proposed Dates: 3rd – 4th September 2004
Venue: C.T.O. Hospital – Lecture Hall – Via San Nemesio No 25 – Roma, ITALY
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SCIENTIFIC COMMITTEE Chairmen, Teachers, Surgeons and Speakers |
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| E. ALFONSO: (Miami-USA) E. BALESTRAZZI : ( Aq- I) C. BOSCHER: (Paris -F) R. BRANCATO: ( Mi -I) M. CAMELLIN: (Ro-I) G. CARELLA: (Pc- I) F. CARONES: (To- I) M. CASELLI: (Lt- I) L. CERULLI: (Rm- I) P. COLLIARDO: (Rm- I) E. CORAZZA: (Rm – I) V. DE MOLFETTA: (Monza – I) C. DI BIASE: (Rm – I) S. DI GIULIO: (Rm – I) G. FALCINELLI: (Rm – I) G.C FALCINELLI: (Rm – I) B. FALSINI: (Rm – I) P. FILADORO: (Rm – I) C. FORLINI: (Ra – I) S. FRUSCELLA: (Rm – I) M. FUKUDA: (Osaka – JPN) C. GENISI: (Pd – I) G. GRABNER: (Salzburg – A) M. GUALDI: (Rm – I)K. HILLE: (Homburg – D) E. LACOMBE: (Paris – F) B. LATTE: (Ss – I) |
C. LIU: (Brighton-GB) L. LUPELLI: (Rm – I) L. MASTROPASQUA: (Ch – I) U. MERLIN: (Ro – I) B. MONACO: (Rm – I) A. MOUNIR: (Cairo-EGYPT) A. NIUTTA: (Rm – I) P. PALUMBO: (Rm – I) J.M PAREL: (Miami-USA) I. PECORELLA: (Rm – I) V. PETITTI: (Rm – I) V. PICARDO: (Rm – I) M. PIOVELLA: (Mi – I) A. POCOBELLI: (Rm – I) P. RAMA: (Mi – I) S. RAO: (Chennai-INDIA) A. RAPIZZI: (Tv – I) V. SARNICOLA: (Gr – I) M. TALONI: (Rm – I) R. TANDON: (New Delhi-INDIA) F. TRIMARCHI: (Rm – I) F. TUCCI: (Rm – I) M. VERGARI: (Rm – I) C.M VILLANI: (Rm – I) P. VINCIGUERRA: (Mi – I) |
| SURGERY OF CORNEAL OPACITIES: EXCIMER LASER, STEM CELLS, KERATOPLASTY | ||||
| Friday 3rd September 2004, morning | ||||
| 08:00-08:30 | Registration |
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| SESSION 1 – Excimer Laser | ||||
| President: U. Merlin – Chairmen: R. Brancato, E. Alfonso, A. Pocobelli | ||||
| LECTURE HALL | ||||
| 8:30-8:40 | Welcome |
U. Merlin, V. Petitti |
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| 8:40-8:55 | Standard and last generation diagnostic instruments in corneal opacities |
L. Mastropasqua |
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| 8:55-9:10 | Corneal opacities suitable to excimer laser treatment | U. Merlin | ||
| 9:10-9:25 | PTK in PRK outcomes | P. Vinciguerra | ||
| 9:25-9:40 | PTK in corneal leucomas | M. Camellin | ||
| 9:40-9:55 | PTK in superficial dystrophies and in corneal erosions | F. Carones | ||
| 9:55-10:10 | PTK after radial keratotomies and keratoplasties | A. Rapizzi | ||
| 10:10-10:20 | Discussion | |||
| SESSION 2: Stem cells and amniotic membrane: state of the art | ||||
| President: E. Balestrazzi – Chairmen: A. Niutta, P. Rama, V. Sarnicola | ||||
| LECTURE HALL | ||||
| 10:20-10:35 | Stem cell autograft |
E. Balestrazzi |
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| 10:35-10:50 | Stem cell allograft | V. Sarnicola | ||
| 10:50-11:05 | Amniotic membrane: indications and limits | P. Rama | ||
| 11:05-11:15 | Welcome by Authorities | |||
| 11:15-11:35 | Coffee break | |||
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| SESSION 3: Keratoplasty | ||||
| President: V. De Molfetta – Chairmen: M. Piovella, M. Gualdi, F. Trimarchi | ||||
| LECTURE HALL | ||||
| 11:35-11:50 | Corneal opacities suitable for keratoplasty | S. Fruscella | ||
| 11:50-12:05 | Mechanized lamellar Keratoplasty | C. Genisi | ||
| 12:05-12:20 | Deep lamellar keratoplasty | F. Trimarchi | ||
| 12:20 -12:35 | Perforating keratoplasty | E. Alfonso | ||
| 12:35 -12:50 | Post-operative management-Rejection | C. Forlini | ||
| 12:50 -1:00 | Medical and legal issues in Italy | F. Tucci | ||
| 1:00 -1:20 | Discussion | |||
| 1:20-2:30 | LUNCH | |||
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| Friday 3rd September 2004, afternoon | ||||
| International Course on Falcinelli’s modified osteodontokeratoprosthesis: surgical techniques, complications and results | ||||
| LECTURE HALL | ||||
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| SESSION 1 – Introduction | ||||
| President: R. Brancato – Chairmen: L. Cerulli, J. M Parel, G. C Falcinelli | ||||
| 2:30-2:40 | Opening remarks | J. M. Parel, G. C. Falcinelli | ||
| 2:40-2:55 | Epidemiology | L. Cerulli | ||
| 2:55-3:10 | Indications and limits of stem cells in corneal blindness | P. Rama | ||
| 3:10-3:20 | High risk PK: functional results – Follow-up | V. De Molfetta | ||
| 3:20-3:30 | Different types of Kpros | E. Alfonso | ||
| 3:30-3:40 | Indication for OOKP and patients’ selection | C. Liu, R. Tandon | ||
| 3:40-3:50 | Electrophysiology | B. Falsini | ||
| 3:50-4:00 | Echography | P. Colliardo | ||
| 4:00-4:10 | Dentists’ role and CT scan | B. Monaco, C. Di Biase | ||
| 4:10-4:20 | Optical cylinder characteristics | L. Lupelli, K. Hille, P. Palumbo | ||
| 4:20-4:30 | OOKP biological properties | M. Caselli | ||
| 4:30-4:50 | Discussion | |||
| 4:50-5:15 | Coffee break | |||
| SESSION 2 – Surgery | ||||
| President: G. Grabner – Chairmen: B. Latte, A. Mounir, V. Picardo | ||||
| LECTURE HALL | ||||
| 5:15-5:25 | Surgical Technique preliminary operation | V. Petitti – M. Vergari | ||
| 5:25-5:40 | 1st Stage: preparation of anterior surface of the eye. Preparation of osteo-odonto-acrylic lamina | G. C. Falcinelli, G. Falcinelli | ||
| 5:40-5:55 | 2nd Stage: implant of osteo-odonto-acrylic lamina in the eye | G. Grabner | ||
| 5:55-6:05 | Histology | I. Pecorella | ||
| 6:05 | Discussion | |||
| Saturday 4th September 2004, morning | ||||
| LECTURE HALL | ||||
| SESSION 3 – Complications in modified OOKP | ||||
| President: E. Lacombe – Chairmen: M. Caselli, V. De Molfetta, C. Liu | ||||
| LECTURE HALL |
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| 8:30-8:45 | Intraoperative complications: 1st and 2nd stages | C. Liu | ||
| 8:45-9:00 | Complications after 1st stage – prevention and treatment | K. Hille | ||
| 9:00-9:15 | Complications after 2nd stage – prevention and treatment | G. C. Falcinelli, G. Falcinelli | ||
| 9:15-9:30 | Choroidal and vitreo-retinal complications | C. Boscher, P. Colliardo | ||
| 9:30-9:40 | Lamina reabsorption – CT scan | G. Grabner | ||
| 9:40-9:50 | Discussion | |||
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| SESSION 4 – Glaucoma in modified OOKP | ||||
| President: C. Boscher – Chairmen: G. Carella, K. Hille, M. Taloni | ||||
| LECTURE HALL |
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| 9:50-10:00 | Glaucoma :diagnosis, frequency, prevention and treatment | M. Taloni, P. Filadoro | ||
| 10:00-10:10 | Cyclodiastasis | G. C. Falcinelli, E. Corazza | ||
| 10:10-10:20 | Retroequatorial antiglaucoma drainage | G. C. Falcinelli, M.Vergari | ||
| 10:20-10:30 | Ahmed’s valve | K. Hille | ||
| 10:30-10:40 | Cycloendophotocoagulation: technique | C. Boscher | ||
| 10:40-10:50 | Cycloendophotocoagulation: complications | C. Forlini | ||
| 10:50-11:00 | Discussion | |||
| 11:00-11:15 | Coffee break | |||
| SESSION 5 – Modified OOKP Results | ||||
| President: J. M. Parel – Chairmen: E. Alfonso, S. Rao, G. C. Falcinelli | ||||
| LECTURE HALL | ||||
| 11:15-12:00 | Anatomo-functional results: Austria, Egypt, Germany, Great Britain, India, Italia, Japan | G. Grabner, A. Mounir, K. Hille, C. Liu, S. Rao, M. Taloni, M. Fukuda | ||
| 12:00-12:10 | Vati index and database | G. Grabner | ||
| 12:10-12:25 | Discussion and conclusions | J. M. Parel, G. C. Falcinelli, G. Grabner | ||
| SESSION 6 – Wet lab | ||||
| President: C. Liu – Chairmen: P. Colliardo, G. Falcinelli, S. Rao | ||||
| ROOM A | ||||
| 12:25-1:15 | OOKP patients’examination (follow-up up to 38 years) | |||
| ROOM B | ||||
| 12:25-1:15 | Modified OOKP. Practice with surgical instruments. For 10 participants (fee 100 €) | |||
| Saturday 4th September 2004, afternoon (optional) | ||||
| Live surgery and videos | ||||
| President: V. Picardo – Chairmen: M. Caselli, C. Liu, M. Taloni | ||||
| 2:30-6:30 | Ahmed’s valve, cyclodiastasis, endophthalmitis, endoscopic cyclophotocoagulation, haemovitreous, lamina explant, mucosa erosion, retina detachment, retroequatorial antiglaucoma drainage, symblepharon | |||
| Note: Operations from the above mentioned pathologies wil be performed live if patients are available. Alternatively surgery of 1st and 2nd stages modified OOKP will be performed live and videos of complications will be shown (fee 50 €). | ||||
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5th KPro- 8th IOSS Joint Meeting, Miami, Florida, USA, 2003
Date:
9 May, 2003
Venue:
Retter Auditorium, Bascom Palmer Eye Institute, University of Miami, School of Medicine, Miami, Florida, USA
Organizers:
Eduardo Alfonso, Jean-Marie Parel, Deborah Sweeney, Scheffer Tseng
Meeting President:
Emmanuel Lacombe
Theme:
Ocular Surface Inflammation As a Threat to Reconstruction and Keratoprosthesis
Synopsis:
Inflammation is a common host response following internal or external insults, and a prelude to formation of granulation and scar tissues. Ocular surface inflammation is no exception but can also be caused by dryness due to the lack of tear film protection and by mechanical friction due to the eyelid blinking when lubricity is lost. Once setting in and becoming persistent, ocular surface inflammation, a hallmark of a number of ocular surface diseases, may produce a vicious cycle leading to destruction of the ocular surface defense with respect to the maintenance of tear film, cicatricial complications to the blink function, and deterioration of epithelial stem cell function. Indeed chronic inflammation has been identified as a high risk factor to surgical reconstruction. In allografts, chronic inflammation facilitates rejection. In keratoprosthesis, the source of inflammation elicited at the interface of host and KPro is at the center stage in KPro design, and presents as a threat to KPro maintenance.
Objective:
The main objective of this joint meeting is to explore deeper the role of ocular surface inflammation in the context of ocular surface reconstruction and keratoprosthesis implantation. After completion of this joint meeting, it is hoped that participants will gain new knowledge and skills that are important to the diagnosis and treatment of ocular surface inflammation so that the success of reconstruction and keratoprosthesis may be promoted.
Program: Friday 9th May 2003
| 07:00 | Registration and breakfast |
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| 08:00 | Welcome to BPEI, address by Chairman |
Carmen Puliafito |
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| 08:10 | Opening Lecture: Role of ocular surface inflammation in tear film disturbance |
Stephen Plugfelder |
SECTION I
THE ROLE OF INFLAMMATION DERIVED FROM THE TEAR FILM ABNORMALITY
Chaired by S. Pflugfelder
| 08:30 | Ocular surface and tear function findings in premature and term babies |
M. Dogru |
| M. Dogru, H. Karakaya, N. Koksal, A. Ozmen, H. Erturk, E. Goto, Y. Matsumoto, K Tsubota |
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| 08:40 | “Sandwich Keratitis” after deep Lamellar Endothelial Keratitis: A new clinical entity |
T. John |
| T. John |
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| 08:50 | Hyperosmolarity stimulates MMPs and inflammatory cytokins via MAPK pathway in human |
D-Q. Li |
| corneal epithelial cells and experimental mouse models |
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| L. De-Quan, H-S. Kim, L. Luo, S. Pflugfelder |
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| 09:00 | Pro and anti-inflammatory forms of Interleukin-1 in the tear fluid and conjunctiva of patients with |
A. Solomon |
| dry eye disease |
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| A. Solomon, D. Dursun, Z. Liu, Y. Xie, A. Macri, S. Pflugfelder |
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| 09:10 | Discussion |
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SECTION II
THE ROLE OF INFLAMMATION DERIVED FROM THE BLINKING ABNORMALITY
Chaired by S. Tseng
| 09:30 | Kinetic analysis of tear interference images to detect blink-induced friction and to guide punctual |
M. Di Pascuale |
| occlusion and replacement of synthetic meibum in different types of dry eye |
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| M. Di Pascuale, M. Edgar, M. Espana, K. Tetsuya, S. Tseng |
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| 09:40 | Eyelid pathologies in Stevens Johnson Syndrome |
E. Espana |
| E. Espana, M. Di Pascuale, T. Kawakita, S. Tseng |
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| 09:50 | Mucous membrane graft and scleral lens to treat eyelid and tarsal pathologies for patients with |
T. Kawakita |
| Stevens Johnson Syndrome |
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| T. Kawakita, M. Di Pascuale, E. Espana, S. Tseng |
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| 10:00 | Intraoperative application of Mitomycin C reduces conjunctival inflammation during amniotic |
S. Tseng |
| membrane transplantation for fornix reconstruction |
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| S. Tseng, M. Di Pascuale, E. Espana, T. Kawakita |
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| 10:10 | Discussion |
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| 10:30 | Coffee / Tea Break |
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| 11:00 | IOSS Honored Guest Lecture: Neurotrophic Keratitis: Current Management Strategies |
Kenneth Kenyon |
SECTION III
THE ROLE OF INFLAMMATION DERIVED FROM THE HOST STROMA
Chaired by E. Alfonso
| 11:20 | In vivo confocal microscopy in the acute phase of corneal inflammation |
A. Kobayashi |
| A. Kobayashi, A. Maeda, Y. Shirao, K. Sugiyama |
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| 11:30 | A case of allergic corneal ulcer in Atopic Keratoconjunctivitis (AKC) persistent for six months that |
Y. Takano |
| healed by amniotic membrane transplantation |
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| Y. Takano, K. Fukagawa, M. Miyake-Kashima, M. Tanaka, J. Shimazaki, K. Tsubota, H. Fujishima |
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| 11:40 | Mitomycin C, Amniotic Membrane Transplantation and Limbal Autograft in Treating Recurrent |
Y-F Yao |
| Pterygia with Severe Symblepharon and Motility Restriction |
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| Yu-Feng Yao, Yong-Ming Zhang, Wen-Ya Qiu, Scheffer C.G. Tseng |
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| 11:50 | Inflammation as a cause of failure of ex-vivo expanded limbal stem cells transplantation |
P. Rama |
| P. Rama |
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| 12:00 | Discussion |
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| 12:20 | Lunch Break and Tour of BPEI |
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| 13:20 | BPEI Honored Guest Lecture: The Collar Button Keratoprosthesis |
Claus Dohlman |
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| 13:40 | KPro Honored Guest Lecture: |
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| Strampelli’s Osteo-Odonto-Keratoprosthesis. Advantages and important technical details |
Joaquin Barraquer |
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| 14:00 | Biological properties of Strampelli’s OOKP and surgical improvements of Falcinelli’s |
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| modified OOKP: Prevention against inflammation |
Giancarlo Falcinelli |
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| 14:20 | Three remarkable KPro histories by Michael Roper-Hall |
Jean-Marie Parel |
SECTION IV
THE ROLE OF INFLAMMATION DERIVED FROM THE INTERFACE BETWEEN THE HOST TISSUE AND THE KPRO
Chaired by D. Sweeney
| 14:40 | Tissue response to mechanical defect of synthetic corneal inlays |
T. Xie |
| R. Xie, M. Evans, D. Sweeney, A. Vannas |
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| 14:50 | Results of the osteo-odonto-keratoprosthesis (OOKP) in severe inflammatory eye diseases |
R. Tandon |
| Experience from the United Kingdom |
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| C. Liu, J. Herold, S. Thorpe, C. Hull, P. Britain, L. Goldberg, R. Tandon |
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| 15:00 | Clinical results of implantation of Dolhman keratoprosthesis at the Bascom Palmer Eye Institute |
V. Fernandez |
| V. Fernandez, R. Wirthlin, E. Spinn, F. Marangon, E. Alfonso |
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| 15:10 | High resolution computer tomography indicates severe absorption of the lamina in |
K. Hille |
| osteo-odonto-keratoporsthesis |
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| K. Hille, R. Seidel, K. Ruprecht |
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| 15:20 | The Pintucci’s Dacron felt. Colonizable KPro in ocular surface inflammation and in dry eye |
S. Pintucci |
| S. Pintucci, F. Pintucci |
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| 15:30 | Melts with AlphaCor: Clinical experiences and the effect of MPG |
C. Hicks |
| C. Hicks for the AlphaCor clinical investigators |
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| 15:40 | Biological response to a SupraDescemetic Synthetic Cornea (sDSC) in rabbits |
J. Stoiber |
| J. Stoiber, V. Fernandez, P. Lamar, S. Dubovy, S. Kaminski, E. Lacombe, B. Duchesne, E. Alfonso, S. Tseng, J-M. Parel | ||
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| 15:50 | Discussion |
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| 16:10 | Coffee / Tea Break |
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SECTION V
CLINICAL EXPERIENCES OF KPRO
Chaired by J-M. Parel
| 16:30 | Report of results with using tooth allografts for osteo-odonto-keratoprosthesis in edentulous |
R. Tandon |
| patients with end-stage ocular surface disease |
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| C. Liu, J. Herold, S. Thorp, . Hull, L. Goldberg, T. Georgiou, R. Tandon |
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| 16:40 | Keratoprosthesis with biocolonizable support: Three years follow-up |
J. Murta |
| J. Murta, M. Quadrado, P. Faria, R. Faria |
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| 16:50 | First experience with the AlphaCor artificial cornea |
G. Grabner |
| G. Grabner, J. Ruckhofer, J. Stoiber |
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| 17:00 | Towards a biomimetic hydrogel keratoprosthesis |
A. Lloyd |
| A. Lloyd, C. Liu, F. Lydon, J. Li, V. Franklin, B. Tighe, S. Sandeman |
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| 17:10 | Supradescemetic Synthetic Cornea (sDSC): Ex-vivo feasibility study in human eye bank eyes |
J. Stoiber |
| J. Stoiber, V. Fernandez, P. Lamar, S. Kaminski, E. Lacombe, B. Duchesne, E. Alfonso, J-M. Parel |
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| 17:20 | Swedged on corneal plane collar button KPro |
T. White |
| T. White |
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| 17:30 | Discussion |
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| 17:40 | Concluding remarks |
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| 18:00 | Cocktails |
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Final Program:
Please click here to download final program and abstracts.
Presenter Information:
Please click here to download.
Registration Fee:
As in past meetings the registration fee is included in the IOSS $ 100 annual membership fee, otherwise it is $100 for non-members, $30 for students, residents and fellows (Letter from mentor is required). For IOSS membership, see www.ioss.org.Please fill out the registration form and fax back immediately to Deborah Sweeney at +61 2 9385 7401.
Suggested Hotels:
Intercontinental (downtown Miami)
100 Chopin Plaza
Miami, Florida
33131
USA
Tel: +1 305 577 1000
Fax: +1 305 577 0384
http://www.intercontinental.com/usa/miami/hotel_miaha.shtml
Marriott Biscayne Bay (downtown Miami)
1633 North Bayshore Drive
Miami, Florida
33132
USA
Tel: +1 305 374 3900
Fax: +1 305 375 0597
http://www.marriott.com/dpp/PropertyPage.asp?MarshaCode=MIABB
Sonesta Beach Resort (Key Biscayne)
350 Ocean Drive
Key Biscayne, Florida
33149
USA
Tel: +1 305 361 2021
Fax: +1 305 361 3096
http://www.sonesta.com/Page.asp?pageid=2103
Ritz Carlton (Key Biscayne)
455 Grand Bay Drive
Key Biscayne, Florida
33149
USA
Tel: +1 305 365 4500
Fax: +1 305 365 4505
http://www.ritzcarlton.com/resorts/key_biscayne/
Please note the organizers cannot book hotel rooms or make travel arrangements for participants.
IOSS-MCLOSA Meeting, London, UK, 2002
Date:
22nd November 2002
Venue:
Royal College of Physicians
11 St Andrews Place
Regent’s Park
London
NW1 4LE
Tel: +44 207 935 1174
Fax: +44 207 487 5218
Organizer:
Christopher Liu
Focus:
Chronic Conjunctival Inflammation – Pathogenesis and Management
See www.mclosa.org.uk for more information or email Christopher Liu for details
INTRODUCTORY COURSE IN OSTEO-ODONTO-KERATOPROSTHESIS (OOKP)
Postgraduate Medical School and The Sussex Eye Hospital Brighton and Sussex University Hospitals Trust
Date:
Wednesday 20 and Thursday 21 November 2002
Venue:
The New Seminar Room
Sussex House
Brighton and Sussex University Hospitals Trust in Brighton
Contact:
Mrs Erica Strange University of Brighton Postgraduate Medical School
Falmer Campus Brighton East Sussex BN1 9PH UK
Telephone: +44 1273 644005 Fax: +44 1273 644002
E-Mail: e.strange@brighton.ac.uk
Organizer:
Christopher Liu
We are pleased to enclose the programme and registration form for this Introductory OOKP Course taking place on 20 and 21 November 2002 in the New Seminar Room, Sussex House, Brighton and Sussex University Hospitals Trust in Brighton.
The Course will comprise a variety of lectures with live surgery, two-way audio/video links (Stage 1 and Stage 2 OOKP Surgery) and examination of patients.
Hotel accommodation can be arranged, and at the end of the first day we will be hosting a Course Dinner at a local French Restaurant.
The final programme is attached (Download doc file 43KB). To book your place please complete the registration form, arrange the necessary payment and return to:
Mrs Erica Strange University of Brighton Postgraduate Medical School
Falmer Campus Brighton East Sussex BN1 9PH UK
Telephone: +44 1273 644005 Fax: +44 1273 644002
E-Mail: e.strange@brighton.ac.uk
It is envisaged that delegates would be attending the joint IOSS-MCLOSA meeting on 22 November 2002 at the Royal College of Surgeons, London. The joint meeting will be on chronic conjunctivitis.
IOSS 10th International Meeting, Grosseto, Tuscany, Italy
The 10th International Meeting of the IOSS will take place – in pleasant surroundings in Tuscany – from June 13th-15th inclusive, in 2002. The Meeting is titled “Corneal Stem Cells: refresher course for clinical use”.
Scheffer Tseng MD, Ph.D, of the Bascom Palmer Eye Institute, Miami, USA; will preside, and the Conference Chairman will be Vincenzo Sarnicola MD Consultant ophthalmologist at the Eye Department at Grosseto’s Hospital, Italy.
Prof. Vincenzo Sarnicola is one of Italy’s most esteemed experts in ocular surface disorders. He is personally convinced that in spite of the great developments in this field, there is still a need for KPro.
OOKP & KPro session
Date:
June 13th-15th, 2002
Provisional program:
June 13th, p.m. Round Table: “KPro update: surgical technique and long-term results”
Live surgery: June 14th a.m. (morning)
Free papers: June 14th p.m. (afternoon)
Discussion of KP problems: June 15th p.m. (afternoon).
Venue: Hotel La Fattoria, Grosseto, Tuscany, Italy and Principiana, a town near Grosseto.
Organizer:
Prof. GC Falcinelli
Via Gregorio VII, 350
00165 Rome, Italy
Fax: +39-06-6623028
Tel: +39-06-5809994
e-mail: Falcinellig@tiscalinet.it
