Past Meetings – 1999-2001
4th KPro STUDY GROUP MEETING
May 4-5, 2001
Fort Lauderdale, Marina Marriott, Florida, USA
Date:
May 4-5, 2001
Organizer:
Bascom Palmer Eye Institute
University of Miami, School of Medicine
Miami, Florida
USA
Venue:
Fort Lauderdale, Marina Marriott, Florida, USA
Friday May 4
Registration
KPro-IOSS status today & introduction of Dr. Sweeney. Jean-Marie Parel
KPro: 34 years later. Michael Roper-Hall
Introduction of Prof. T.T. Sun. Scheffer CG Tseng
Introduction of Prof. Claes Dohlman. Eduardo Alfonso
Session I: KERATOPROSTHESIS
Chair: C Dohlman – Moderator: E Alfonso
KPro Study Group Keynote lecture
Do a PK? Do a KPro? Do nothing? The uncertain borders between indications. Claes Dohlman
Modified Osteo-odonto-keratoprosthesis for treatment of corneal blindness: Long-term anatomic and functional outcome in 181 cases. Giancarlo C Falcinelli
Osteo-odonto-keratoprosthesis. Francesco Lannetti
The osteo-odonto-keratoprosthesis – resume of six years operative experience. Konrad Hille
Medium term visual and retention results of modern osteo-odonto-keratoprosthesis (OOKP). Padmanabha P Syam
A model for international skills transfer for OOKP surgery. Christopher Liu
Advantages of self-graft tibial keratoprosthesis (KPT). Jose Temprano Acedo
Thirty years of experience with the stainless steel anchored artificial cornea champagne cork KP. Jan G F Worst
20 years experience with the Pintucci’s keratoprosthesis. Stefano Pintucci
Biocolonization: Early success and late disillusions. Emmanuel Lacombe
Experience with Lacombe PCL5 KPro at the Ain Shams Shams University – Egypt. Amira Mounir
Chirila KPro I: An overview. Geoffrey J Crawford
Chirila KPro II: Case histories. Donald Tan
Chirila KPro III: Keratoprosthesis or not? Celia R Hicks
Results of leukomas biokeratoprosthetics using prostheses with the peripheral part made of various donor tissues. Yury Y Kalinnikov
Surgical treatment of secondary glaucoma by keratoprosthesis. Stanislav A Yakimenko
Session II OCULAR SURFACE RECONSTRUCTION
Chair: SCG Tseng – Moderator: K Tsubota
IOSS Keynote Lecture:
Corneal epithelial stem cells: Markers, kinetic regulation and development flexibilities. Tung-Tien Sun
Restoration of neuroanatomic integration of ocular surface defense as a first step of ocular surface reconstruction. Scheffer CG Tseng
Amniotic membrane transplantation associated with limbal conjuctival transplantation for ocular surface reconstruction in Stevens-Johnson syndrome. Jose AP Gomes
Amniotic membrane transplantation associated or not with limbal-conjuctival transplantation for ocular surface reconstruction in chemical burn. Myrna S Santos
Treatment of severe ocular surface disorders with corneal epithelial stem cell transplantation. Kazuo Tsubota
Factors influencing surgical outcome of ocular surface reconstruction. Jun Shimakazi
Long-term results of kerarolimbal allografts with or without penetrating keratoplasty for total limbal stem cell deficiency. Abraham Solomon
The effect of amniotic membrane and limbal autograft transplantation for the patients with recurrent ptergium and pseudoptergium associated with symblepharon. Tae Hoon Choi
Changes in human corneas after amniotic membrane transplantation. A correlative light and transmission electron microscopy study. Josef Stoiber
Keratoprosthesis or keratoplasty and surface reconstruction: How to choose? John Dart
Saturday May 5
Registration
Session III OSR & KPro POSTER PRESENTATION
Chair: J Dart – Moderator: G Grabner
Surgical management of refractory palpebral allergic conjuctivitis. Quresh B Muskati
AMT for unusual corneal deposits in homocystinuria. Srinivas K Rao
Histology of non-extruding OOKP laminae. Christopher Liu
Can we implant our keratoprosthesis for humans as a temporary use? Hiroshi Shiota
Comparison of infection rates in patients following amniotic membrane transplant (AMT) and keratoprosthesis. Eduardo C Alfonso
Endophthalmitis in patients with keratoprosthesis: Incidence, bacterial etiologies and risk factors. Mahnaz Nouri
Osteo-odonto-keratoprosthesis modified: Long-term results in dry eyes. Giancarlo Falcinelli
Retroprosthesis membranes as complications after keratoprosthesis. Stanislav A Yakimenko
Evaluation of bone reduction of the haptic lamina in osteo-odonto-keratoprosthesis by computerized tomography. Josef Stoiber
Management of vitreoretinal complications in eyes with permanent keratoprosthesis. Subhransu Ray
Corneal blindness from end-stage sjorgrens syndrome. Case reports. Eric J Dudenhoefer
Long-term results of pump shunt implant for refractory glaucoma. Thomas C White
Biointegration of the dacron felt colonizable Pintucci’s keratoprosthesis, in vitro and in vivo studies plan. Stefanno Pintucci
Coralline Hydoxyapatite keratoprosthesis. Carlos Leon
Keratoprosthesis in a seeing eye – a case report. Quresh B Maskati
An in vivo model for assessment of epithelial overgrowth of synthetic onlays. RZ Xie
Experiments with keratoprostheis (“Artificial cornea”). Mahnaz Nouri
Costs and gains of complex procedures in rehabilitation of end stage Stevens- Johnson syndrome. Gerd Geerling
Session IV THE FUTURE: OSR? KPros? Or both?
Chair: JM Parel – Moderator: Ray JF Tsai
Introduction of Dr. May Griffith Scheffer CG Tseng
Biocornea Invited Lecture:
Corneal tissue equivalents for replacement of damaged corneas. May Griffith
Ex vivo expansion of limbal stem cells for corneal surface reconstruction. Ray Jui-Fang Tsai
Cultivated corneal epithelial transplantation in severe stem cell deficiencies. Shigeru Kinoshita
The step-wise operation used in vivo grown corneal epithelium on amniotic membrane in patient’s own eye in acute corneal burn injury. Jae Chan Kim
Evaluation of the limbus stem cell concept by a gene analytic procedure. Konrad Hille
Transplantation of the autologous submandibular gland for absolute dry eyes. Gerd Geerling
Development of a newly designed double-fixed Seoul-type keratoprosthesis. Mee Kum Kim
How to cope with decolonization and necrosis to prevent extrusion. Emmanuel Lacombe
A new supradescemetic keratoprosthesis: A novel design. Stephan Kaminski
In vivo examination of surface modified polymers used as potential hap keratoprosthesis. Eike Berger
In vivo preliminary screening of novel KPro materials & Towards a synthetic OOKP. Andrew W Lloyd
Synthetic polymer as a corneal onlay. Debbie F Sweeney
Conclusions: Alfonso, Tseng, Parel, Sweeney
3rd KPro Study Group Meeting, Birmingham, England
3rd KPro STUDY GROUP MEETING
June 24-26, 1999
University of Birmingham Conference Park
Birmingham, England
Focus: Role of the haptic in increasing KPro long term survival
Meeting Executive President: Michael J. Roper-Hall
Poster Coordination: Peter McDonnell & Kira Brenman
KPro’99 Scientific Coordinator: Kira Brenman
“Proceedings may be found An Inst Barraquer 2001, 30 (1-2) :”
Presentations at the 3rd KPro Study Group Meeting
Friday June 25, 1999
Introduction.
Michael Roper-Hall, University of Birmingham, England
Contributions of past KPro conferences and the future.
J-M Parel for the KPro Study Group Steering Committee
Early experience and present views on keratoprosthesis.
Joaquin Barraquer, Instituto Barraquer, Spain.
Session I Clinical results of 1st generation KPros
(Monobloc, synthetics)
Chairs: Lacombe & Polack, Moderator: Dohlman
Success and failure of 1st generation KPros.
Michael Roper-Hall, University of Birmingham, England
KPro in non-cicatrizing conditions.
Claes Dohlman, Mass. Eye and Ear, USA
Ceramic KPro, long term follow-up.
Frank Polack, G Heimke, University of Florida, University of South Florida, USA
All PMMA retroprosthetic fixation KPro at 10 years.
Emmanuel Lacombe, Rothschild Foundation, France
Session II: Clinical results of 2nd generation KPros
(OOKP, biologic skirt)
Chairs: Falcinelli & Barraquer, Moderator: Grabner
Falcinelli’s OOKP KPro – 15 years experience.
Giancarlo Falcinelli, P Colliardo, E Corazza, M Taloni, Foundation for OOKP, Italy
Long-term success in OOKP: Can VATI give more comparable results? A proposal for a method to compare “Medium to Long-term” outcome as demonstrated by the Salzburg OOKP series.
Gunther Grabner, J Stoiber, J Ruckhofer, G Falcinelli, Eye Clinic Salzburg, Austria
Early British results of modern Falcinelli OOKP surgery.
Andrea Sciscio, C Liu, Sussex Eye Hospital/University of Brighton, England
OOKP- surgical management and results.
Konrad Hille, H Landau, KW Ruprecht, University of Saarland, Germany
Complications in OOKP.
Maurizio Taloni, G Falcinelli, B Falsini, P Filadoro, V Petitti, OOKP Foundation, Italy
A new lens for vitreous and retinal surgery in OOKP patients.
Jeroni Nadal, J Barraquer, Instituto Barraquer, Spain
Session III Clinical results of 3nd generation KPros
(Metals & synthetics, donor tissue integration)
Moderator: Kain
Evaluation of 46 KPros after 6 years. Follow-up.
Mihai Pop, Emergency Eye Hospital, Romania
Worst KPro.
Jan Worst, MV van Andel. Jan Worst Research Group, Holland
KPro in terminal stages of edematous bullous keratopathy.
Stanislav A Yakimenko, Filatov Institute of Eye Diseases & Tissue Therapy, Ukraine
Visual recovery in Mooren’s ulcer by scleral grafting and KPro.
YP Henry, MJW Zaal, HJ Volker-Dieben, Free University, Netherlands
Paralimbal scleral window;
Indu R Singh, Amritsar, India
Session IV Clinical results of 4th generation KPros
(Synthetic biointegration)
Chairs: Pintucci, Moderator: Crawford
Girard KPro (commented Video).
Louis Girard, Houston, USA (presented in his absence by Parel and Brenman)
PMMA/Dacron biointegrated KPro: 19 years experience.
Stefano Pintucci, F Pintucci, A Sarra, Azienda Ospedaliera, S. Giovanni-Addolorata, Centro Oftalmologico Pintucci, Italy
Role of hydromechanical fixation in haptic biocolonization.
Emmanuel Lacombe, Rothschild Foundation, France
Pilot study of Chirila KPro in humans.
Celia Hicks, GJ Crawford, TV Chirila, X Lou, S Platten, S Vijayasekaran, IJ Constable, Lions Eye Institute, Australia
Aachen KPro – 1st prolonged application.
Norbert I Schrage, S Kompa, S Langefeld, B Kirchhof, University of Aachen, Germany
Evaluation of biocolonizable keratoprosthesis in patients with corneal edema.
Isabelle Riss, University of Bordeaux, France
Session V Expulsion and methods to prevent it
Chairs: Lacombe & Caldwell, Moderator: Alfonso
Risk Factors for endophthalmitis in KPro patients.
Mahnaz Nouri, H Terada, ML Durand, E Alfonso, CH Dohlman, Mass Eye & Ear, USA and Bascom Palmer Eye Institute, USA
Transplantation of the autologous submandibular gland for severe keratoconjunctivitis sicca in Stevens-Johnson syndrome.
Gerd Geerling, JRO Collin, IA Cree, MM Matheson, JKG Dart, Moorfields Eye Hospital, England
Immunological & biochemical indices of blood in patients with RPM after KPro.
Olga Guseva, L Velichko, T Metelitsina, SA Yakimenko, Filatov Institute of Eye Diseases & Tissue Therapy, Ukraine
Glaucoma following KPro.
Claes Dohlman, Mass. Eye and Ear, USA
The Ahmed glaucoma valve in secondary glaucoma in OOKP.
Konrad Hille, H Landau, KW Ruprecht, University of Saarland, Germany
Successful treatment of KPro skirt exposure using a transpositional conjunctival-lower eyelid retractor complex flap.
John Cowden, JW Gigantelli, Mason Eye Institute, USA
Clinical indications and action mechanisms of amniotic membrane transplantation for ocular surface reconstruction in patients being considered for a keratoprosthesis.
Eduardo C Alfonso, SCG Tseng, Bascom Palmer Eye Institute, USA
Saturday June 26, 1999
Session VI Research and Future directions
Chairs: Hicks & Duchesne, Moderator: Parel
Assessment of Corneal Mechanics of Humans, Pigs and Cats. Comparison with Keratoprosthesis Polymers.
Bernard Duchesne, R Bougaran, D Durand, H Tahi, University of Liege, Belgium; Bascom Palmer Eye Institute, USA
Biocompatibility evaluation of new non-porous transparent materials for keratoprosthesis.
Hassan Tahi, B Duchesne, Bascom Palmer Eye Institute, USA; University of Liege, Belgium
Ocular biomaterials: Cellular & surface chemical issues.
Brian Tighe, Aston University, Birmingham, UK
Development of new synthetic material for corneal replacements.
Valerie Franklin, F Lydon, K Evans, B Tighe, C Liu, Aston University, England
Does embryonic keratocyte EK1.BR models corneal wound healing with age?
Susan Sandeman, RGA Faragher, M Allen, C Liu, AW Llyod, University of Brighton, England
Effect of aging on KPro biointegration.
Susan Sandeman, RGA Faragher, M Allen, C Liu, AW Llyod, University of Brighton, England
In-vitro study of silicone foam and ePTFE as potential haptic materials for KPro
Eike Berger, K Gaebert, J Saedler, CF Kreiner, R Guthoff, University of Rostock, Germany
Evaluation of ceramic KPro in rabbits.
Hiroshi Shiota, H Eguchi, H Yunoki, H Amitani, University of Tokushima, Japan
Hydroxyapatite coralline keratoprosthesis: First human cases.
Carlos Leon, Guatemala
Session VII Summary of poster presentation
Chairs: Falcinelli & Rol, Moderator: Barraquer
Clinical results of 1st to 4th generation KPros
OOKP in the treatment of corneal blindness due to “dry eye”.
Paulo Colliardo, M Caselli, GC Falcinelli, G Grabner, I Micozzi, Foundation for OOKP, Italy
Visual fields with an OOKP.
Chris Hull, DF Edgar, C Liu, A Sciscio, City University, England
Influence of PMMA diameter on visual field in OOKP.
Konrad Hille, H Landau, KW Ruprecht, University of Saarland, Germany
Design of OOKP optic-improving field of vision.
Chris Hull, DF Edgar, C Liu, A Sciscio, City University, England
OOKP: New design of optical cylinder.
Giancarlo Falcinelli, R Fletcher, L Lupelli, P Palumbo, F Sala, Foundation for OOKP, Italy
Aachen KPro-1st temporary application.
Sirpa Kompa, S Langefeld, B Kirchhof, NF Schrage, University of Aachen, Germany
Posterior fixation keratoprosthesis with biocolonizable seal: 6 years, 47 patients.
Emmanuel Lacombe, J-C Joyaux, I Riss, B Duchesne, H Tahi, J-M Parel, Rothschild Foundation, France & Universities of Miami, Bordeaux, Liege, and Paris
Preoperative prognostic factors in keratoprosthesis.
F Yaghouti, M Nouri, WC Fung, WJ Power, MJ Doane, CH Dohlman. Mass Eye&Ear Infirmary and Schepens Eye Research Institute, USA
Research and Future directions
Human and porcine cornea.
Katrin Gaebert, E Berger, J Saedler, DG Weiss, R Guthoff, University of Rostock, Germany
Cartilage to cornea: structural & cellular issues in material design for KPros.
Fiona Lydon, PH Corkhill, JH Fitton, VJ Franklin, HR Oxley, BJ Tighe, Aston University, England
A new prosthetic corneal graft.
Thomas White, University of South Dakota, USA
Marine inspired artificial cornea.
David Green, F Lydon, B Tighe, C Liu, Aston University, England
Ophthalmic biomaterials: Inflammatory role of vitronectin.
Brian Tighe, VJ Franklin, C Graham, A Mann, M Guillon, Aston University, England
Biosurface structures: Nature’s solutions.
Steve Tonge, B Tighe, Aston University, England
Aston biomaterials research unit: A profile.
Valerie Franklin et al, Aston University, England
Invited presentation: Once upon a time there was a blind.
Jean-Christophe Joyaux, Martinique, FWI
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